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Pediatric Dermatology

Tinea Capitis

Confirm suspected scalp dermatophyte infection with hair and scale microscopy or culture when feasible, begin systemic therapy because topical agents do not reach the follicular infection, identify inflammatory kerion promptly to limit permanent alopecia, and interrupt household transmission with contact assessment and sporicidal shampoo.

Clinical question: How should clinicians confirm, treat, and contain tinea capitis while recognizing kerion and alternative scalp disorders?

First Visit

Identify cases requiring immediate systemic treatment

Scalp involvement changes management because topical treatment alone will not eradicate follicular infection.

Start oral antifungal therapy when the clinical pattern is compatible with tinea capitis, particularly in a prepubertal child with scalp scale, broken hairs, patchy alopecia, pustules, or inflammatory swelling. Tinea capitis occurs primarily in prepubertal children but can occur at any age, including adulthood. publications aapTinea Capitis (Ringworm of the Scalp) - AAP Publicationspublications aapTinea Capitis (Ringworm of the Scalp) | Red Book - AAP Publications The dermatophyte penetrates the follicular outer root sheath and may invade the hair shaft; therefore, topical antifungal monotherapy is ineffective. publications aapSuperficial Fungal Infections | Pediatrics In Review - AAP PublicationsPubMedTinea Capitis - StatPearls - NCBI Bookshelfcomposer publications aapRed Book - AAP

Escalate urgency for a painful, boggy, pustular scalp plaque or nodule consistent with kerion. This inflammatory form can result in permanent alopecia, unlike typical noninflammatory tinea capitis. PubMedTinea Capitis - StatPearls - NCBI Bookshelf Obtain mycologic specimens before or at treatment initiation when possible, but do not defer systemic therapy for culture results in a clinically convincing kerion. Oral griseofulvin, terbinafine, itraconazole, or fluconazole may be required for kerion, with anti-inflammatory treatment considered as an adjunct rather than a replacement for antifungal therapy. WileyThe kerion: an angry tinea capitis - John - 2018 - Wiley Online LibraryWileyBritish Association of Dermatologists' guidelines for the ...PubMedTinea Capitis - StatPearls - NCBI Bookshelf

Clinical branch points at presentation
PresentationMost useful immediate actionWhat changes next
Scaly alopecic scalp lesion with broken hairsCollect scalp scale and affected hairs for KOH microscopy and fungal culture; initiate systemic therapy when clinical suspicion is high. ScienceDirectTrichophytosis - an overview | ScienceDirect TopicsOxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...publications aapSuperficial Fungal Infections | Pediatrics In Review - AAP PublicationsCulture identifies the causative dermatophyte and supports adjustment if the clinical response is inadequate. Oxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...ScienceDirectFirst report of kerion (tinea capitis) caused by combined Trichophyton mentagrophytes and Microsporum canis
Painful boggy plaque, pustules, or marked inflammatory swellingTreat as kerion with an oral antifungal; consider a short systemic corticosteroid course as adjunctive anti-inflammatory therapy. WileyBritish Association of Dermatologists' guidelines for the ...PubMedTinea Capitis - StatPearls - NCBI BookshelfPrompt treatment aims to reduce inflammation-associated risk of permanent alopecia. PubMedTinea Capitis - StatPearls - NCBI Bookshelf
Scalp scaling but no alopecia or hair-shaft findingsPerform KOH examination and culture rather than relying on clinical appearance alone. ScienceDirectTrichophytosis - an overview | ScienceDirect TopicsOxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...A negative mycologic evaluation should redirect assessment toward nondermatophyte scalp disease.

Confirmation

Use KOH microscopy and culture correctly

Specimen quality determines whether testing meaningfully changes treatment selection and follow-up.

Sample active scalp scale and plucked affected hairs for direct microscopy and fungal culture. KOH examination can provide immediate confirmation, whereas culture is required for definite identification in selected infections and permits species-level assessment. ScienceDirectTrichophytosis - an overview | ScienceDirect TopicsOxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...ScienceDirectCurrent concepts in systemic and topical therapy for superficial mycoses - ScienceDirect KOH dissolves keratin and permits visualization of fungal septate hyphae; reported KOH sensitivity and specificity are 61% and 95%, respectively, with performance dependent on specimen quality and examiner technique. ScienceDirectPotassium Hydroxide - an overview

Use Wood lamp examination as a supplemental, not exclusionary, test. Some ectothrix Microsporum infections fluoresce blue-green, but T tonsurans—the leading U.S. cause—does not fluoresce. ScienceDirectPotassium Hydroxide - an overviewpublications aapTinea Capitis (Ringworm of the Scalp) - AAP Publicationspublications aapTinea Capitis (Ringworm of the Scalp) | Red Book - AAP PublicationsPubMedIn vitro pharmacodynamic characteristics of griseofulvin against dermatophyte isolates of Trichophyton tonsurans from tinea capitis patients - PubMed A negative Wood lamp examination therefore does not rule out tinea capitis in U.S. practice.

Interpretation of commonly used mycologic tests
TestPositive resultImportant limitationClinical use
KOH microscopyFungal septate hyphae visible after keratin dissolution. ScienceDirectPotassium Hydroxide - an overviewReported sensitivity is 61%; a negative result does not exclude infection. ScienceDirectPotassium Hydroxide - an overviewRapid confirmation from scale or hair specimens. ScienceDirectTrichophytosis - an overview | ScienceDirect TopicsScienceDirectPotassium Hydroxide - an overview
Fungal cultureDermatophyte growth permits causative-organism identification. Oxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...ScienceDirectFirst report of kerion (tinea capitis) caused by combined Trichophyton mentagrophytes and Microsporum canisDoes not provide immediate treatment guidance in a clinically convincing kerion.Confirm infection and identify organism, especially after negative microscopy or treatment failure. Oxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...ScienceDirectCurrent concepts in systemic and topical therapy for superficial mycoses - ScienceDirect
Wood lampBlue-green fluorescence supports selected Microsporum ectothrix infections. ScienceDirectPotassium Hydroxide - an overviewT tonsurans does not fluoresce and is the predominant U.S. pathogen. ScienceDirectPotassium Hydroxide - an overviewpublications aapTinea Capitis (Ringworm of the Scalp) - AAP Publicationspublications aapTinea Capitis (Ringworm of the Scalp) | Red Book - AAP PublicationsAdjunctive examination; never use a negative result to exclude tinea capitis. ScienceDirectPotassium Hydroxide - an overview

Alternative diagnoses requiring different tests

When a groin eruption accompanies the scalp complaint, distinguish tinea from candidiasis and erythrasma by site-specific examination and microscopy. Erythrasma produces coral-red Wood lamp fluorescence and has negative KOH preparation and fungal culture, whereas tinea cruris is evaluated with KOH or culture. ScienceDirectDermatophyte - an overview | ScienceDirect Topics This Wood lamp finding pertains to erythrasma, not to routine exclusion of tinea capitis.

Drug Therapy

Select and dose oral antifungal therapy

Systemic therapy is required; treatment choice should incorporate organism data, formulation, and clinical response.

Griseofulvin remains a core first-line systemic option. Use microsize griseofulvin 15-20 mg/kg orally once daily, maximum 1 g/day, or ultramicrosize griseofulvin 5-10 mg/kg orally once daily, maximum 750 mg/day. Give griseofulvin after a meal containing fat to optimize administration. composer publications aapRed Book - AAP A typical course is 4-6 weeks and should continue for 2 weeks beyond clinical resolution. composer publications aapRed Book - AAP Another clinical reference describes systemic therapy courses of 4-8 weeks, supporting reassessment based on clinical and mycologic response rather than a fixed calendar endpoint alone. PubMedTinea Capitis - StatPearls - NCBI Bookshelf

Terbinafine is an oral alternative, and continuous dosing has demonstrated high mycologic cure rates; griseofulvin and terbinafine are both supported therapies for tinea capitis. WileyAn update on tinea capitis in children - Gupta - Wiley Online LibraryPubMedTinea Capitis - StatPearls - NCBI Bookshelf Organism identification is clinically useful because treatment duration may vary by dermatophyte: one review describes 2-4 weeks for Trichophyton infections and 8-12 weeks for Microsporum infections. ScienceDirectTinea Capitis: Trends in Spain - ScienceDirect.com Do not infer species from a negative Wood lamp examination, because the common U.S. organism T tonsurans does not fluoresce. ScienceDirectPotassium Hydroxide - an overviewPubMedIn vitro pharmacodynamic characteristics of griseofulvin against dermatophyte isolates of Trichophyton tonsurans from tinea capitis patients - PubMed

Reserve itraconazole or fluconazole as oral alternatives when a standard agent is unsuitable or response is inadequate, with species confirmation and reassessment of the diagnosis. WileyThe kerion: an angry tinea capitis - John - 2018 - Wiley Online LibraryPubMedTinea Capitis - StatPearls - NCBI Bookshelf Available excerpts do not provide regimen-specific doses, renal adjustments, hepatic monitoring schedules, or contraindication algorithms for terbinafine, fluconazole, or itraconazole; use current product labeling and local prescribing guidance before selecting these agents.

Systemic treatment options supported in the cited literature
AgentDose and duration supported hereSelection considerations
Microsize griseofulvin15-20 mg/kg orally once daily; maximum 1 g/day; usually 4-6 weeks and continue 2 weeks beyond clinical resolution. composer publications aapRed Book - AAPAdminister with a fatty meal; established systemic therapy for tinea capitis. composer publications aapRed Book - AAPPubMedIn vitro pharmacodynamic characteristics of griseofulvin against dermatophyte isolates of Trichophyton tonsurans from tinea capitis patients - PubMed
Ultramicrosize griseofulvin5-10 mg/kg orally once daily; maximum 750 mg/day. composer publications aapRed Book - AAPUse the formulation-specific dose; do not substitute microsize and ultramicrosize doses. composer publications aapRed Book - AAP
TerbinafineContinuous oral dosing is reported to achieve high mycologic cure rates; no regimen-specific dose is provided here. WileyAn update on tinea capitis in children - Gupta - Wiley Online LibraryOral alternative; culture may guide duration because Trichophyton and Microsporum courses may differ. WileyAn update on tinea capitis in children - Gupta - Wiley Online LibraryScienceDirectTinea Capitis: Trends in Spain - ScienceDirect.com
Itraconazole or fluconazoleOral alternatives; no regimen-specific dose is provided here. WileyThe kerion: an angry tinea capitis - John - 2018 - Wiley Online LibraryPubMedTinea Capitis - StatPearls - NCBI BookshelfConsider when griseofulvin or terbinafine is unsuitable or after inadequate response with reassessment. WileyThe kerion: an angry tinea capitis - John - 2018 - Wiley Online LibraryPubMedTinea Capitis - StatPearls - NCBI Bookshelf

Inflammatory Disease

Manage kerion without mistaking inflammation for treatment failure

Kerion requires antifungal eradication plus control of severe inflammation.

A kerion is the inflammatory presentation of tinea capitis and may present as a painful nodular or boggy scalp lesion with pustules. PubMedTinea Capitis - StatPearls - NCBI BookshelfScienceDirectFirst report of kerion (tinea capitis) caused by combined Trichophyton mentagrophytes and Microsporum canis Because inflammatory tinea capitis may result in scarring alopecia, begin systemic antifungal therapy promptly and document baseline alopecia and the distribution of inflammatory disease for response assessment. PubMedTinea Capitis - StatPearls - NCBI Bookshelf

Consider short-course systemic corticosteroids as adjunctive anti-inflammatory therapy for kerion or severe id reactions; corticosteroids do not replace oral antifungal treatment. WileyBritish Association of Dermatologists' guidelines for the ...PubMedTinea Capitis - StatPearls - NCBI Bookshelf Reassess after treatment initiation for reduced pain, swelling, pustulation, and progression of alopecia. Persistent or progressive disease should trigger repeat fungal sampling and verification of the causative organism. Oxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...cks nice org ukScenario: Management of fungal skin infection - scalp - CKS - NICE

Kerion treatment priorities
PriorityActionReason
Eradicate dermatophyte infectionStart an oral antifungal agent. WileyThe kerion: an angry tinea capitis - John - 2018 - Wiley Online LibraryPubMedTinea Capitis - StatPearls - NCBI BookshelfThe infection is follicular and cannot be adequately treated with topical therapy alone. publications aapSuperficial Fungal Infections | Pediatrics In Review - AAP PublicationsPubMedTinea Capitis - StatPearls - NCBI Bookshelf
Limit inflammationConsider a brief systemic corticosteroid adjunct for kerion or severe id reaction. WileyBritish Association of Dermatologists' guidelines for the ...PubMedTinea Capitis - StatPearls - NCBI BookshelfInflammatory tinea capitis may lead to permanent alopecia. PubMedTinea Capitis - StatPearls - NCBI Bookshelf
Confirm unresolved diseaseRepeat skin and hair sampling when response is inadequate. cks nice org ukScenario: Management of fungal skin infection - scalp - CKS - NICECulture and microscopy can identify persistent dermatophyte infection and causative organism. Oxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...ScienceDirectFirst report of kerion (tinea capitis) caused by combined Trichophyton mentagrophytes and Microsporum canis

Containment

Reduce household spread and manage school attendance

Transmission control accompanies systemic treatment and targets ongoing shedding and shared fomites.

Examine siblings and other household contacts for evidence of tinea capitis. composer publications aapRed Book - AAP One clinical reference recommends treating asymptomatic individuals and using antifungal or selenium shampoo for 2-4 weeks to interrupt ongoing transmission. PubMedTinea Capitis - StatPearls - NCBI Bookshelf Recommend that household members avoid sharing combs, brushes, ribbons, hats, and other hair-care items. composer publications aapRed Book - AAP

Use selenium sulfide shampoo or an antifungal shampoo as adjunctive shedding reduction, not as curative monotherapy. PubMedTinea Capitis - StatPearls - NCBI Bookshelfcomposer publications aapRed Book - AAP Children receiving treatment can attend school and usual activities; school exclusion is not required simply because tinea capitis is diagnosed. composer publications aapRed Book - AAP Instruct affected children not to share combs, hair brushes, hats, or hair ornaments with classmates until treatment has begun. composer publications aapRed Book - AAP

At follow-up, assess clinical resolution and adherence to the full systemic course. For griseofulvin, treatment is usually continued for 2 weeks beyond clinical resolution. composer publications aapRed Book - AAP If disease remains active, repeat scalp and hair sampling and reassess the organism, treatment duration, and competing diagnosis rather than extending treatment without reevaluation. Oxford Academicsingle-centre, retrospective cohort study of paediatric tinea capitis in ...cks nice org ukScenario: Management of fungal skin infection - scalp - CKS - NICE

Transmission-control actions for index patients and contacts
TargetActionTiming
Index patientBegin systemic antifungal therapy and add selenium sulfide or antifungal shampoo to reduce shedding. PubMedTinea Capitis - StatPearls - NCBI Bookshelfcomposer publications aapRed Book - AAPAt diagnosis; shampoo is adjunctive, not definitive treatment. PubMedTinea Capitis - StatPearls - NCBI Bookshelf
Household contactsExamine for tinea capitis; asymptomatic individuals may be treated with antifungal or selenium shampoo. PubMedTinea Capitis - StatPearls - NCBI Bookshelfcomposer publications aapRed Book - AAPUse shampoo for 2-4 weeks when used for transmission control. PubMedTinea Capitis - StatPearls - NCBI Bookshelf
School and sports settingPermit usual attendance during treatment; prohibit sharing hair implements and accessories. composer publications aapRed Book - AAPAfter treatment has started. composer publications aapRed Book - AAP

References

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