Editorial standards

Evidence should remain visible.

Astra clinical guides are original evidence syntheses designed for physicians and medical trainees. They are educational references, not patient-specific medical advice or substitutes for clinical judgment.

Source selection

Research prioritizes current U.S. professional-society guidelines, regulatory information, pivotal trials, systematic reviews, and high-quality primary literature. Every cited source remains linked from the guide so readers can inspect the underlying evidence.

Preparation

Astra uses frontier language models within a structured clinical research workflow to retrieve, compare, and synthesize source material. Models are instructed not to invent evidence and to distinguish guidelines, randomized evidence, observational findings, and expert consensus.

Review status

Each guide displays its update date. A clinical-review label and reviewer attribution appear only when a reviewer is explicitly recorded; publication or automated preparation alone is not represented as clinical review.

Updates and corrections

Clinical recommendations can change. Readers should verify recommendations against current guidance, drug labeling, local policy, and patient-specific factors. Corrections or source concerns can be sent to outreach@astramd.org.