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Cardiac Electrophysiology

Supraventricular Tachycardia

Manage suspected SVT by first identifying instability and QRS regularity, using vagal maneuvers and adenosine for stable regular narrow-complex rhythms, avoiding inappropriate AV-nodal blockade in pre-excited arrhythmias, and offering electrophysiology study with ablation for recurrent symptomatic disease.

Clinical question: How should clinicians classify, terminate, and prevent recurrence of supraventricular tachycardia?

Acute Care

Classify instability before attempting rhythm termination

The first decision is whether the tachycardia itself is causing inadequate perfusion.

Obtain a 12-lead ECG whenever feasible, continuous rhythm monitoring, blood pressure, and assessment for hypotension, heart failure, chest pain, or altered mental status. These findings identify poorly tolerated SVT and support immediate treatment and arrhythmia-specialist referral rather than observation alone. ScienceDirectParoxysmal Supraventricular Tachycardia - an overviewACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

For hemodynamically unstable SVT, perform synchronized electrical cardioversion. If the patient is stable enough for an initial attempt at vagal maneuvers or adenosine, cardioversion remains indicated when these measures are ineffective, contraindicated, or not feasible. ScienceDirectParoxysmal Supraventricular Tachycardia - an overviewACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

Use ECG regularity and QRS width as safety gates. A regular narrow-complex tachycardia is the setting for an AV-nodal intervention strategy. A regular wide-complex tachycardia may be ventricular tachycardia, SVT with aberrancy, or accessory-pathway conduction; if the mechanism is uncertain, manage it as an undifferentiated wide-complex tachycardia rather than reflexively administering AV-nodal blockers. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI Bookshelf

ECG and stability features that determine the immediate SVT pathway. ScienceDirectParoxysmal Supraventricular Tachycardia - an overviewPubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
PresentationImmediate interpretationNext action
Hypotension, heart failure, chest pain, or altered mental status with SVTHemodynamically unstable tachyarrhythmia. ScienceDirectParoxysmal Supraventricular Tachycardia - an overviewSynchronized cardioversion; use vagal maneuvers or adenosine only if clinically feasible without delaying definitive stabilization. ScienceDirectParoxysmal Supraventricular Tachycardia - an overviewACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
Regular narrow-complex tachycardia, stableLikely AVNRT, orthodromic AVRT, or regular atrial tachycardia/flutter. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfVagal maneuvers and/or IV adenosine; consider IV beta-blocker, diltiazem, or verapamil if needed. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
Wide-complex tachycardia or uncertain mechanismCould be ventricular tachycardia, aberrant SVT, or accessory-pathway conduction. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfAvoid assuming benign SVT; treat as undifferentiated wide-complex tachycardia when diagnosis is uncertain. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI Bookshelf
Irregular narrow-complex tachycardiaConsider atrial fibrillation, flutter with variable block, multifocal atrial tachycardia, or ectopy rather than typical regular PSVT. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfDo not apply the regular-SVT termination pathway without defining the rhythm and considering pre-excitation. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI Bookshelf

Acute Treatment

Terminate stable regular narrow-complex SVT with AV-nodal interventions

Use interventions that transiently slow or block AV nodal conduction while preserving diagnostic information.

For stable regular SVT of unknown mechanism, perform vagal maneuvers and/or administer IV adenosine as first-line treatment. Initial management of regular narrow-complex tachycardia is generally directed at slowing AV nodal conduction. BMJDiagnosis and management of supraventricular tachycardia - The BMJACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

If adenosine is ineffective, not feasible, or the rhythm recurs, IV beta-blocker, IV diltiazem, or IV verapamil is an alternative for stable regular SVT. In one emergency-department study of spontaneous SVT, slowly infused verapamil or diltiazem converted 98% compared with 86.5% for adenosine; mean post-conversion blood pressure fell with calcium-channel blockers, and hypotension occurred in 1 of 102 patients receiving a calcium-channel blocker. ScienceDirectSlow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardiaACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

When choosing a nondihydropyridine calcium-channel blocker, avoid rapid bolus administration in patients with marginal blood pressure. Historical rapid infusion was associated with hypotensive episodes; a slow-infusion study used verapamil at 1 mg/min and diltiazem at 2.5 mg/min, with conversion exceeding 97% and hypotension in approximately 1% of participants. ScienceDirectSlow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardia - ScienceDirectScienceDirectSlow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardia

Acute treatment sequence for stable regular SVT. BMJDiagnosis and management of supraventricular tachycardia - The BMJScienceDirectParoxysmal Supraventricular Tachycardia - an overviewScienceDirectSlow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardiaACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
StepInterventionDecision consequence
1Vagal maneuvers. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITIf terminated, obtain a sinus-rhythm ECG and determine recurrence burden before selecting preventive therapy. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
2IV adenosine. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITTermination supports an AV-node-dependent mechanism but is not diagnostic; transient AV block may reveal atrial tachycardia. PubMedElectrocardiographic Diagnosis of Atrial Tachycardia: Classification, P‐Wave Morphology, and Differential Diagnosis with Other Supraventricular Tachycardias - PMC
3If refractory or recurrent: IV beta-blocker, diltiazem, or verapamil in a stable patient. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITChoose cautiously when blood pressure is vulnerable; slow calcium-channel blocker infusion has been studied as an alternative approach. ScienceDirectSlow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardia - ScienceDirectScienceDirectSlow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardia
4Synchronized cardioversion when drug therapy fails, is contraindicated, or is infeasible. ScienceDirectParoxysmal Supraventricular Tachycardia - an overviewACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITAfter conversion, pursue mechanism documentation and definitive therapy for recurrent symptomatic episodes. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI BookshelfACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

Use adenosine as a diagnostic maneuver

Adenosine or a vagal maneuver transiently suppresses AV nodal conduction and may expose otherwise obscured atrial activity, helping identify atrial tachycardia when the ECG diagnosis is uncertain. Failure to terminate with AV nodal block favors an atrial tachycardia that is continuing independently of the AV node; however, adenosine can terminate focal atrial tachycardia caused by triggered activity or microreentry as well as AVNRT and AVRT. PubMedElectrocardiographic Diagnosis of Atrial Tachycardia: Classification, P‐Wave Morphology, and Differential Diagnosis with Other Supraventricular Tachycardias - PMC

ECG Phenotyping

Separate AVNRT, AVRT, atrial tachycardia, and pre-excited rhythms

Mechanism changes medication safety, ablation target, and urgency of electrophysiology referral.

AVNRT and AVRT are common reentrant causes of PSVT. AVNRT depends on fast and slow AV nodal pathways, whereas AVRT uses an accessory pathway; ablation therefore targets the AV nodal slow pathway for AVNRT and the accessory pathway for AVRT. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI Bookshelfpublications aapLong-Term Clinical Outcomes From Catheter Ablation of SVT

A resting ECG showing manifest pre-excitation should trigger arrhythmia-specialist referral. In a patient with WPW pattern and a stable regular narrow tachycardia consistent with orthodromic AVRT, use vagal maneuvers followed by adenosine as first-line therapy; beta-blockers or calcium-channel blockers are described as second-line agents, with cardioversion reserved for refractory rhythm. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

Do not extrapolate the orthodromic AVRT pathway to a wide-complex rhythm with possible pre-excitation or aberrancy. In this setting, uncertainty about rhythm mechanism is itself a reason to avoid routine AV-nodal blockade and use a wide-complex tachycardia approach. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI Bookshelf

Suspect atrial tachycardia when abnormal P waves are identifiable or become apparent during transient AV block, particularly in patients with structural heart disease. Surface ECG interpretation and Holter analysis can refine the diagnosis and can direct mapping to anatomic regions of interest when catheter ablation is planned. PubMedElectrocardiographic Diagnosis of Atrial Tachycardia: Classification, P‐Wave Morphology, and Differential Diagnosis with Other Supraventricular Tachycardias - PMCACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

Mechanism-focused clues and management implications in SVT. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI BookshelfPubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfPubMedElectrocardiographic Diagnosis of Atrial Tachycardia: Classification, P‐Wave Morphology, and Differential Diagnosis with Other Supraventricular Tachycardias - PMCACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
Likely mechanismActionable clueWhat it changes
AVNRTAbrupt episodes with neck pulsation; regular narrow-complex tachycardia is typical. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITAV-nodal termination strategy is appropriate when stable; definitive ablation targets the slow pathway. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI Bookshelf
Orthodromic AVRTWPW pattern in sinus rhythm plus regular narrow tachycardia. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfVagal maneuvers then adenosine are first-line; refer for accessory-pathway assessment and ablation discussion. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfPubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI Bookshelf
Focal atrial tachycardiaAtrial activity becomes visible during adenosine-induced or vagal AV block; structural heart disease increases suspicion. PubMedElectrocardiographic Diagnosis of Atrial Tachycardia: Classification, P‐Wave Morphology, and Differential Diagnosis with Other Supraventricular Tachycardias - PMCACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITDo not infer mechanism solely from adenosine termination; use ECG/Holter characterization to plan mapping and treatment. PubMedElectrocardiographic Diagnosis of Atrial Tachycardia: Classification, P‐Wave Morphology, and Differential Diagnosis with Other Supraventricular Tachycardias - PMC
Possible pre-excited or aberrant wide-complex tachycardiaWide QRS or uncertainty whether conduction is via an accessory pathway. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI BookshelfAvoid assuming a regular-SVT pathway; manage as undifferentiated wide-complex tachycardia. PubMedWolff-Parkinson-White Syndrome - StatPearls - NCBI Bookshelf

Recurrence Prevention

Choose ablation or medical suppression based on symptoms, pre-excitation, and patient preference

A documented episode should lead to a mechanism-specific plan rather than repeated unscheduled acute care.

Offer electrophysiology study and catheter ablation as first-line definitive treatment for symptomatic PSVT when the patient is an ablation candidate and prefers a curative strategy. Contemporary sources describe excellent success with relatively low complication rates for AVNRT and AVRT, and ablation can reduce recurrent hospitalization and reliance on long-term medication. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI BookshelfPubMedSupraventricular Tachycardia - StatPearls - NCBI Bookshelf - NIH

For regular SVT of unknown mechanism, patients who are candidates for and prefer ablation should undergo electrophysiology study with catheter ablation. If medical therapy is selected, beta-blockers, diltiazem, or verapamil are options only in the absence of pre-excitation; flecainide or propafenone are options in the absence of structural heart disease. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

For patients who cannot undergo or decline ablation and do not respond to simpler agents, amiodarone, dofetilide, or sotalol are listed as lower-strength ongoing options; digoxin is an option only when pre-excitation is absent. These drugs require individualized selection because the source algorithm does not provide dosing or monitoring specifications. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

Manifest pre-excitation materially lowers the threshold for electrophysiology referral. Ablation may be considered even without symptoms when the accessory pathway has a short refractory period, and is strongly recommended for high-risk occupations. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI Bookshelf

Ongoing management choices after documented regular SVT. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI BookshelfACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
Clinical situationPreferred next stepImportant restriction
Symptomatic recurrent PSVT; patient accepts procedureElectrophysiology study and catheter ablation. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI BookshelfACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITDefine mechanism because AVNRT requires slow-pathway ablation and AVRT requires accessory-pathway ablation. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI Bookshelf
No pre-excitation; medical therapy selectedBeta-blocker, diltiazem, or verapamil. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITUse only when pre-excitation is absent. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
No structural heart disease; medical therapy selectedFlecainide or propafenone may be considered. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITDo not apply this option when structural heart disease is present. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT
Manifest pre-excitationArrhythmia-specialist referral and ablation discussion. PubMedParoxysmal Supraventricular Tachycardia - StatPearls - NCBI BookshelfACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKITAvoid the routine no-pre-excitation drug pathway. ACC[PDF] SUPRAVENTRICULAR TACHYCARDIA (SVT) TOOLKIT

Pregnancy

For PSVT during pregnancy, adenosine is the first-choice acute agent because of its very short half-life. IV metoprolol or propranolol are second-choice options; use verapamil cautiously when adenosine or beta-blockers are ineffective or contraindicated because of hypotension risk. Synchronized cardioversion is an option when drug therapy is ineffective or contraindicated. Wolters KluwerParoxysmal supraventricular tachycardia in... : Bali Journal of Anesthesiology

References

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