{ "schemaVersion": 2, "eyebrow": "Dermatology", "title": "Seborrheic Dermatitis", "summary": "Manage seborrheic dermatitis clinically when distribution is typical, but perform targeted fungal testing or biopsy for atypical, refractory, or systemic presentations. Use site-directed antifungal therapy for control, brief anti-inflammatory treatment for flares, and maintenance therapy to reduce relapse.", "seoDescription": "Physician guide to diagnosing, differentiating, treating, and maintaining control of adult and pediatric seborrheic dermatitis.", "clinicalQuestion": "How should clinicians confirm, treat, maintain, and escalate care for seborrheic dermatitis across scalp, face, body, and pediatric presentations?", "specialty": "Dermatology", "audience": "U.S. physicians and medical trainees", "tags": [ "seborrheic dermatitis", "dandruff", "cradle cap", "ketoconazole shampoo", "scalp dermatitis", "sebopsoriasis", "tinea capitis" ], "keyTakeaways": [ "Typical seborrheic dermatitis is a clinical diagnosis; reserve KOH examination, fungal culture, or biopsy for morphology, distribution, age, treatment response, or systemic findings that suggest a competing diagnosis. [9][12][14]", "For adult scalp disease, ketoconazole 1% to 2% shampoo twice weekly for 4 weeks is a supported initial regimen; ketoconazole 2% shampoo once weekly has evidence for relapse prevention. [9]", "Use topical antifungals as the core treatment and add a mild- to moderate-potency topical corticosteroid briefly for inflammatory flares; topical calcineurin inhibitors for facial disease are off-label. [9][11]", "In infants, cradle cap commonly resolves by 5 to 6 months even without treatment; persistent, widespread, hemorrhagic, petechial, or systemically associated disease requires reassessment for alternate diagnoses, including Langerhans cell histiocytosis. [4][17]" ], "sections": [ { "id": "diagnostic-approach", "eyebrow": "Diagnosis", "heading": "When clinical diagnosis is sufficient and when to test", "intro": "Use morphology, site, age, and treatment response to determine whether apparent SD needs confirmation or diagnostic expansion.", "paragraphs": [ "Diagnose SD clinically when greasy scale with erythema is confined to typical seborrheic sites—scalp, central face, retroauricular skin, and upper chest—and the course is recurrent. Routine laboratory or instrumental testing is seldom required. [1][9][14]", "Obtain a KOH preparation from active scale when an annular advancing border, central clearing, alopecia, broken hairs, pustules, satellite lesions, or an atypical distribution raises concern for dermatophyte infection, tinea versicolor, or candidiasis. A positive KOH supports a fungal alternative or coexisting infection and should redirect treatment; KOH may also identify yeast forms in candidiasis. [2][18]", "Perform a skin biopsy when lesions remain diagnostically ambiguous after examination and targeted fungal evaluation, when psoriasis and SD coexist or cannot be distinguished clinically, or when presumed SD is severe, atypical, and unresponsive to local therapy. Scalp psoriasis more often shows neutrophilic parakeratosis, spongiform micropustules of Kogoj, and clubbed evenly elongated rete ridges; SD more often shows follicular plugging, shoulder parakeratosis, and prominent lymphocytic exocytosis. [13][14]" ], "bullets": [ "In a child after infancy but before puberty, do not assume isolated scalp scale is SD; prioritize tinea capitis, atopic dermatitis, and psoriasis in the differential. [12]", "Use dermoscopy as an adjunct when demodicosis or rosacea is plausible: SD shows patchy dotted vessels with fine yellow scale, whereas erythematotelangiectatic and papulopustular rosacea show linear vessels in a polygonal network. [3]", "Consider HIV or other immunodeficiency, neurologic disease, cardiac disease, and alcoholic pancreatitis as predisposing contexts when SD is unusually extensive or difficult to control. [23]" ], "subsections": [], "table": { "caption": "Clinical patterns that should change the diagnostic pathway. [2][12][13][17]", "columns": [ "Presentation", "Leading alternative or concern", "Immediate diagnostic action", "Finding that changes management" ], "rows": [ [ "Annular scaly plaque with raised border and central clearing", "Tinea corporis", "KOH examination of scale. [2]", "Positive KOH supports dermatophyte treatment rather than SD-directed therapy alone. [2]" ], [ "Scalp scale in a prepubertal child, especially with hair-shaft involvement", "Tinea capitis", "KOH examination or fungal culture from hair shaft. [12][18]", "Confirmed fungal infection requires management as tinea capitis. [18]" ], [ "Scalp-limited thick scale or plaque without other diagnostic sites", "Psoriasis versus SD", "Biopsy if the distinction will alter treatment and remains unclear clinically. [13][14]", "Psoriatic histology favors psoriasis-directed management; follicular plugging and shoulder parakeratosis favor SD. [13]" ], [ "Infant with petechiae, hemorrhagic lesions, lymphadenopathy, systemic symptoms, or failure of appropriate local therapy", "Langerhans cell histiocytosis or another systemic disorder", "Urgently reassess diagnosis and pursue biopsy-based evaluation. [12][17]", "These findings should not be attributed to uncomplicated cradle cap. [17]" ] ] } }, { "id": "adult-treatment", "eyebrow": "Initial Treatment", "heading": "Site-directed treatment for adults", "intro": "Select a topical antifungal foundation, then add anti-inflammatory therapy only when erythema or pruritus requires faster flare control.", "paragraphs": [ "For mild-to-moderate adult scalp SD, begin ketoconazole 1% to 2% shampoo twice weekly for 4 weeks. Other supported topical classes include ciclopirox or miconazole formulations, mild- to moderate-potency topical corticosteroids, and keratolytic or humectant agents such as propylene glycol. [9]", "For limited facial or body disease, use topical ketoconazole, ciclopirox, or clotrimazole. Mild- to moderate-potency topical corticosteroids can be used for inflammatory disease; choose the shortest effective exposure because SD is recurrent and treatment frequently becomes intermittent. [9][23]", "Topical calcineurin inhibitors are an off-label option for facial SD when steroid exposure is undesirable or repeated anti-inflammatory treatment is needed. Pimecrolimus 1% cream is not approved for SD, although it is used in practice for this indication. [9][11]" ], "bullets": [ "Use ketoconazole 2% foam twice daily for 4 weeks for an adult topical regimen with reported continued twice-daily use for up to 12 months and a high safety profile in the reviewed evidence. [9]", "Ketoconazole 2% gel twice weekly for 4 weeks and ketoconazole 2% foaming gel twice weekly for 1 month followed by once weekly are additional scalp formulations described for adult disease. [9]", "Avoid treating a treatment-resistant eruption by serially escalating topical corticosteroid potency before reconsidering tinea, psoriasis, contact dermatitis, demodicosis, or an immunologic/systemic contributor. [2][3][13][23]" ], "subsections": [ { "heading": "Maintenance after control", "paragraphs": [ "Plan maintenance at the first successful response because adult SD relapses. Ketoconazole 2% shampoo once weekly for 6 months reduced relapse in the cited adult scalp data; a separate treatment table recommends once-weekly ketoconazole or ciclopirox maintenance after induction. [9][5]" ], "bullets": [ "Reassess a patient who fails an adequate induction course for adherence, product application, concomitant psoriasis or fungal infection, and the need for diagnostic testing rather than simply extending empiric therapy. [9][13][14]" ] } ], "table": { "caption": "Supported topical regimens for adult seborrheic dermatitis. [5][9]", "columns": [ "Site and clinical use", "Regimen", "Maintenance or key limitation" ], "rows": [ [ "Scalp, initial antifungal treatment", "Ketoconazole 1% to 2% shampoo twice weekly for 4 weeks. [9]", "Ketoconazole 2% shampoo once weekly for 6 months has evidence for relapse prevention. [9]" ], [ "Scalp, alternative antifungal treatment", "Ciclopirox 1% twice daily for 4 weeks. [5]", "Then once weekly in the cited treatment table. [5]" ], [ "Scalp, inflammatory flare", "Mild- to moderate-potency topical corticosteroid as an anti-inflammatory option. [9]", "Use as a flare-directed adjunct rather than a stand-alone long-term strategy. [9][23]" ], [ "Face or body, limited disease", "Ketoconazole, ciclopirox, or clotrimazole topical therapy. [9]", "Add a mild- to moderate-potency topical corticosteroid when inflammation warrants it. [9]" ], [ "Face, recurrent steroid-sparing treatment", "Topical calcineurin inhibitor. [9]", "Off-label for SD; pimecrolimus is not indicated for SD. [11]" ] ] } }, { "id": "refractory-and-severe-disease", "eyebrow": "Escalation", "heading": "Approach to severe, resistant, or extensive disease", "intro": "Failure of topical treatment should trigger diagnostic reassessment before systemic treatment.", "paragraphs": [ "Classify disease as refractory only after confirming that the eruption is SD rather than scalp psoriasis, dermatophyte infection, candidiasis, contact dermatitis, rosacea, or demodicosis. Re-examine the distribution, perform KOH testing when fungal disease is plausible, and biopsy persistent diagnostically uncertain plaques. [2][3][13][14]", "For severe or resistant adult SD, oral therapies have been reported, including itraconazole, terbinafine, fluconazole, ketoconazole, prednisone, and isotretinoin; however, the summarized evidence includes open trials and case reports for several agents, and professional society guidelines and SD-specific labeled treatment options remain limited. Systemic treatment should therefore be reserved for selected refractory cases after diagnostic confirmation and specialist-level risk assessment. [5][6][9]", "Do not use an unusually severe presentation solely as a reason to intensify topical therapy. Evaluate for relevant predispositions, including HIV infection, neurologic disease such as Parkinson disease, neurologic injury, ischemic heart disease, and alcoholic pancreatitis, when clinical context supports that workup. [23][24]" ], "bullets": [ "A concurrent psoriasis phenotype may represent sebopsoriasis; biopsy can be useful when two conditions obscure the clinical diagnosis. [14]", "If an anti-inflammatory agent appears effective but lesions recur immediately or spread beyond classic seborrheic areas, reassess for an alternate diagnosis instead of assuming uncontrolled SD. [12][13][14]" ], "subsections": [], "table": { "caption": "Escalation triggers and next actions for apparent treatment failure. [2][3][6][13][14][23]", "columns": [ "Trigger", "Next action", "Why it matters" ], "rows": [ [ "No meaningful response after an appropriate topical antifungal course", "Review application and adherence; perform KOH examination if tinea, tinea versicolor, or candidiasis is plausible. [2]", "Fungal infections can mimic or coexist with SD. [2]" ], [ "Thick, sharply demarcated scalp plaques or diagnostic uncertainty with psoriasis", "Biopsy when clinical examination cannot distinguish psoriasis from SD. [13][14]", "Histopathology can identify features favoring either disease. [13]" ], [ "Facial papules, pustules, or prominent vascular pattern", "Use dermoscopy and reassess for rosacea or demodicosis. [3]", "These disorders have distinguishable dermoscopic vascular patterns. [3]" ], [ "Severe or extensive recurrent SD with relevant history", "Assess for associated immunodeficiency or systemic/neurologic predisposition as clinically indicated. [23][24]", "HIV, neurologic disease, cardiac disease, and alcoholic pancreatitis are reported predisposing conditions. [23]" ] ] } }, { "id": "pediatric-disease", "eyebrow": "Pediatrics", "heading": "Cradle cap and pediatric seborrheic dermatitis", "intro": "Age and systemic findings determine whether conservative management is appropriate or whether presumed SD needs investigation.", "paragraphs": [ "For uncomplicated infantile scalp SD, counsel that the condition is generally favorable and may completely resolve by 5 to 6 months without treatment. This expectation supports a conservative approach when the infant is otherwise well and lesions are limited to typical greasy scalp scale. [4][7]", "For infant scalp disease requiring treatment, options listed for mild disease include selenium sulfide 2.5% shampoo, zinc pyrithione 1% to 2% shampoo, ciclopirox 1% shampoo or 0.77% gel, and ketoconazole 1%. Hydrocortisone 1% liniment or 0.1% lotion is listed for moderate-to-severe scalp disease; for non-scalp involvement, ciclopirox 1% cream or ketoconazole 1% cream is listed for mild disease and hydrocortisone 1% liniment or cream for moderate-to-severe disease. [8]", "Treatment evidence in infantile SD remains uncertain, and there is no consensus treatment recommendation. Avoid automatically treating all cradle cap aggressively when the disease is asymptomatic and self-limited; use medication when extent or inflammation justifies intervention and reassess if it does not improve. [7][8]" ], "bullets": [ "In adolescents, mild scalp options listed include salicylic acid 3% shampoo, tar 1% to 2% shampoo, selenium sulfide 2.5% shampoo, zinc pyrithione 1% to 2% shampoo, and ketoconazole 1% to 2% shampoo. [8]", "For pediatric lesions that are unresponsive to appropriate local therapy or accompanied by petechiae, hemorrhagic lesions, lymphadenopathy, or systemic symptoms, evaluate for Langerhans cell histiocytosis rather than persisting with empiric SD treatment. [12][17]", "In darker pigmented skin, SD may show hypopigmentation with less visible erythema; assess scale, distribution, and inflammatory change rather than relying on erythema alone. [17]" ], "subsections": [], "table": { "caption": "Pediatric decision points in presumed seborrheic dermatitis. [4][8][12][17]", "columns": [ "Patient pattern", "Management direction", "Escalation threshold" ], "rows": [ [ "Well infant with localized greasy scalp scale", "Expectant management is reasonable because complete resolution by 5 to 6 months may occur without treatment. [4]", "Escalate if disease becomes extensive, atypical, or fails appropriate local management. [12][17]" ], [ "Infant with moderate or severe scalp inflammation", "Hydrocortisone 1% liniment or 0.1% lotion is listed as a treatment option. [8]", "Reconsider diagnosis if there is inadequate response. [12]" ], [ "Prepubertal child with scalp scaling", "Assess for tinea capitis, atopic dermatitis, and psoriasis. [12]", "Use KOH examination or fungal culture from hair shaft when tinea capitis is suspected. [18]" ], [ "Any child with hemorrhagic lesions, petechiae, lymphadenopathy, or systemic symptoms", "Pursue alternate diagnostic evaluation, including consideration of Langerhans cell histiocytosis. [17]", "Do not manage as routine SD. [17]" ] ] } } ], "faq": [], "references": [ { "number": 1, "title": "Differential microRNA profiles in elderly males with seborrheic dermatitis | Scientific Reports", "detail": "www.nature.com", "url": "https://www.nature.com/articles/s41598-022-24383-3", "authors": "www.nature.com", "host": "www.nature.com" }, { "number": 2, "title": "KOH Test - an overview", "detail": "www.sciencedirect.com", "url": "https://www.sciencedirect.com/topics/medicine-and-dentistry/koh-test", "authors": "www.sciencedirect.com", "host": "www.sciencedirect.com" }, { "number": 3, "title": "Entodermoscopy Update : Indian Dermatology Online Journal", "detail": "journals.lww.com", "url": "https://journals.lww.com/idoj/fulltext/2021/12020/entodermoscopy_update__a_contemporary_review_on.2.aspx", "authors": "journals.lww.com", "host": "journals.lww.com" }, { "number": 4, "title": "Pediatric Dermatitis Seborrhoica - A Clinical and... : Indian Dermatology Online Journal", "detail": "journals.lww.com", "url": "https://journals.lww.com/idoj/fulltext/2024/15030/pediatric_dermatitis_seborrhoica___a_clinical_and.3.aspx", "authors": "journals.lww.com", "host": "journals.lww.com" }, { "number": 5, "title": "Child and Adult Seborrheic Dermatitis: A Narrative Review of the ...", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11909311", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov" }, { "number": 6, "title": "Evidence and recommendations on seborrhoeic dermatitis - Guidelines on the Treatment of Skin and Oral HIV-Associated Conditions in Children and Adults - NCBI Bookshelf", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/books/NBK305403", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov" }, { "number": 7, "title": "Interventions for infantile seborrhoeic dermatitis (including cradle cap) - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC6397947", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov" }, { "number": 8, "title": "Pediatric Dermatitis Seborrhoica - A Clinical and Therapeutic Review", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11152465", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov" }, { "number": 9, "title": "An Overview of the Diagnosis and Management of Seborrheic ...", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC9365318", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov" }, { "number": 10, "title": "Seborrheic Dermatitis - StatPearls - NCBI Bookshelf - NIH", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/books/NBK551707", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov" }, { "number": 11, "title": "Pimecrolimus for the Treatment of Adults With Atopic Dermatitis, Seborrheic Dermatitis, or Psoriasis: A Review - CADTH Report / Project in Briefs - NCBI Bookshelf", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/books/NBK481570", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov" }, { "number": 12, "title": "Differential Diagnosis of Seborrheic Dermatitis | Pediatrics In Review | American Academy of Pediatrics", "detail": "pedsinreview.aappublications.org", "url": "https://pedsinreview.aappublications.org/content/7/7/204", "authors": "pedsinreview.aappublications.org", "host": "pedsinreview.aappublications.org" }, { "number": 13, "title": "Histopathological Differential Diagnosis of Psoriasis and Seborrheic Dermatitis of the Scalp - 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CDC", "detail": "ftp.cdc.gov", "url": "https://ftp.cdc.gov/pub/health_statistics/nchs/dataset_documentation/NAMCS/2010/doc2010.pdf", "authors": "ftp.cdc.gov", "host": "ftp.cdc.gov" }, { "number": 21, "title": "[PDF] 2011 National Hospital Ambulatory Medical Care Survey ... - CDC", "detail": "ftp.cdc.gov", "url": "https://ftp.cdc.gov/pub/health_statistics/nchs/dataset_documentation/NHAMCS/doc11.pdf", "authors": "ftp.cdc.gov", "host": "ftp.cdc.gov" }, { "number": 22, "title": "Malassezia yeasts in seborrheic dermatitis scalp in a ... - PubMed", "detail": "pubmed.ncbi.nlm.nih.gov", "url": "https://pubmed.ncbi.nlm.nih.gov/29484095", "authors": "pubmed.ncbi.nlm.nih.gov", "host": "pubmed.ncbi.nlm.nih.gov" }, { "number": 23, "title": "Seborrhoeic dermatitis - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3275327", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov" }, { "number": 24, "title": "Optimizing Treatment Approaches in Seborrheic Dermatitis - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3579488", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov" } ], "editorialNote": "Prepared from cited clinical literature using Astra's research workflow. Verify recommendations against current guidance and patient-specific factors.", "citations": [ { "number": 1, "title": "Differential microRNA profiles in elderly males with seborrheic dermatitis | Scientific Reports", "detail": "www.nature.com", "url": "https://www.nature.com/articles/s41598-022-24383-3", "authors": "www.nature.com", "host": "www.nature.com", "snippet": "Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease worldwide1.\"),2.\"). Clinically, SD is characterized by erythematous greasy patches with yellowish scales on seborrheic areas such as the scalp, face, upper chest, and retroauricular area and can affect people of various ages an", "score": 0.5380859 }, { "number": 2, "title": "KOH Test - an overview", "detail": "www.sciencedirect.com", "url": "https://www.sciencedirect.com/topics/medicine-and-dentistry/koh-test", "authors": "www.sciencedirect.com", "host": "www.sciencedirect.com", "snippet": "### Differential diagnosis\n\nThe main clinical differential diagnoses are tinea corporis/pedis/cruris, intertrigo, cutaneous candidiasis, tinea versicolor, and seborrheic dermatitis. Complicating matters, the bacterial and fungal diseases can coexist, as will be discussed in a later section. Inverse ", "score": 0.8399576 }, { "number": 3, "title": "Entodermoscopy Update : Indian Dermatology Online Journal", "detail": "journals.lww.com", "url": "https://journals.lww.com/idoj/fulltext/2021/12020/entodermoscopy_update__a_contemporary_review_on.2.aspx", "authors": "journals.lww.com", "host": "journals.lww.com", "snippet": "It is possible to dermoscopically differentiate demodex disorders from their main differential diagnosis like seborrheic dermatitis (comprises of dotted vessels in a patchy distribution and fine yellowish scales), erythematotelangiectatic rosacea (shows linear vessels arranged in a polygonal network", "score": 0.5504388 }, { "number": 4, "title": "Pediatric Dermatitis Seborrhoica - A Clinical and... : Indian Dermatology Online Journal", "detail": "journals.lww.com", "url": "https://journals.lww.com/idoj/fulltext/2024/15030/pediatric_dermatitis_seborrhoica___a_clinical_and.3.aspx", "authors": "journals.lww.com", "host": "journals.lww.com", "snippet": "Differential diagnoses in infants are napkin dermatitis, atopic dermatitis, psoriasis, Darier’s disease, keratosis lichenoides chronica, Langerhans cell histiocytosis, etc., [Table 1].[33-35] In adolescents, in addition to face and neck dermatitis, lupus erythematosus, rosacea, contact dermatitis, a", "score": 0.514718 }, { "number": 5, "title": "Child and Adult Seborrheic Dermatitis: A Narrative Review of the ...", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11909311", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "This review explores the current treatment landscape for SD, examining both established and emerging therapies, while considering the unique challenges posed by the condition’s diverse presentations across different patient populations. Treatment recommendations are outlined in Table1.Table 1Summary", "score": 0.76659125 }, { "number": 6, "title": "Evidence and recommendations on seborrhoeic dermatitis - Guidelines on the Treatment of Skin and Oral HIV-Associated Conditions in Children and Adults - NCBI Bookshelf", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/books/NBK305403", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov", "snippet": "## 5.5. Research gaps\n\nThe areas of additional research for seborrhoeic dermatitis identified include:\n\n Well-designed, prospective, blinded RCTs in HIV-infected adults and children to provide high quality evidence upon which to base clinical decision-making;\n Establishment of a standardized outcome", "score": 0.73207545 }, { "number": 7, "title": "Interventions for infantile seborrhoeic dermatitis (including cradle cap) - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC6397947", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "Compared to Cochrane Reviews of adult seborrhoeic dermatitis, there was a dearth of evidence, particularly high‐quality evidence, for ISD. A wider range of interventions have been tested for adults, including, for example, calcineurin inhibitors, azole therapies, lithium, and calcipotriol (Kastarine", "score": 0.7038554 }, { "number": 8, "title": "Pediatric Dermatitis Seborrhoica - A Clinical and Therapeutic Review", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11152465", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "Keywords:_Adolescents_, _dermatitis seborrhoica_, _infants_, _pathogenesis_, _treatment_\n\n## (syn. seborrheic dermatitis, seborrheic eczema) is an inflammatory dermatosis of the erythemato-squamous type, which occurs in infants and adults. The term was coined by Paul Gerson Unna in 1897, who differ", "score": 0.7001783 }, { "number": 9, "title": "An Overview of the Diagnosis and Management of Seborrheic ...", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC9365318", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "In adults, the use of topical agents with antifungal (ketoconazole, ciclopirox, miconazole), antiinflammatory (betamethasone valerate, clobetasol propionate) or keratolytic/humectant (propylene glycol) properties is strongly recommended (Table 1).21–24Table 1Recommended Pharmacological Topical Agent", "score": 0.5999311 }, { "number": 10, "title": "Seborrheic Dermatitis - StatPearls - NCBI Bookshelf - NIH", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/books/NBK551707", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov", "snippet": "24.\n: Augustin M, Kirsten N, Körber A, Wilsmann-Theis D, Itschert G, Staubach-Renz P, Maul JT, Zander N. Prevalence, predictors and comorbidity of dry skin in the general population. J Eur Acad Dermatol Venereol. 2019 Jan;33(1):147-150. [PubMed: 29953684]\n\n25.\n: Hald M, Arendrup MC, Svejgaard EL", "score": 0.5035894 }, { "number": 11, "title": "Pimecrolimus for the Treatment of Adults With Atopic Dermatitis, Seborrheic Dermatitis, or Psoriasis: A Review - CADTH Report / Project in Briefs - NCBI Bookshelf", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/books/NBK481570", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov", "snippet": "## Issue\n\nIn light of the expanded clinical use of pimecrolimus, a review\nof the clinical and cost-effectiveness of its use in adults for the\nmanagement of atopic dermatitis, seborrheic dermatitis, and\npsoriasis will be useful for informing treatment decisions.\n\n## Methods\n\nA limited literature sear", "score": 0.44912744 }, { "number": 12, "title": "Differential Diagnosis of Seborrheic Dermatitis | Pediatrics In Review | American Academy of Pediatrics", "detail": "pedsinreview.aappublications.org", "url": "https://pedsinreview.aappublications.org/content/7/7/204", "authors": "pedsinreview.aappublications.org", "host": "pedsinreview.aappublications.org", "snippet": "# Differential Diagnosis of Seborrheic Dermatitis. Dermatology Service, Veterans Administration Medical Center, and Departments of Dermatology and Pediatrics, University of California School of Medicine, San Francisco. Search for other works by this author on:. *Pediatr Rev* (1986) 7 (7): 204–211. W", "score": 0.72698855 }, { "number": 13, "title": "Histopathological Differential Diagnosis of Psoriasis and Seborrheic Dermatitis of the Scalp - PubMed", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/pubmed/27489423", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov", "snippet": "Title: Histopathological Differential Diagnosis of Psoriasis and Seborrheic Dermatitis of the Scalp - PubMed\nAn official website of the United States government. **The .gov means it’s official.**. Federal government websites often end in .gov or .mil. sharing sensitive information, make sure you’re ", "score": 0.6461259 }, { "number": 14, "title": "Seborrheic dermatitis: Diagnosis and treatment", "detail": "www.aad.org", "url": "https://www.aad.org/public/diseases/a-z/seborrheic-dermatitis-treatment", "authors": "www.aad.org", "host": "www.aad.org", "snippet": "To diagnose this condition, your dermatologist will:\n\n Ask about your symptoms.\n Review your medical history with you, asking if you have allergies or other medical conditions.\n Look closely at the skin with signs of seborrheic dermatitis.\n\nThat’s often all that’s needed to diagnose seborrheic derma", "score": 0.5832277 }, { "number": 15, "title": "Seborrheic Dermatitis - AAP Publications", "detail": "publications.aap.org", "url": "https://publications.aap.org/monograph/chapter-pdf/1781652/ch54.pdf", "authors": "publications.aap.org", "host": "publications.aap.org", "snippet": "Diagnosis confirmed by mineral oil preparation performed on scrapings from lesions or by dermoscopy. Langerhans cell histiocytosis. • Erythematous, yellow or", "score": 0.57723385 }, { "number": 16, "title": "Fungal Skin Infections - AAP Publications", "detail": "publications.aap.org", "url": "https://publications.aap.org/pediatricsinreview/issue-pdf/825736", "authors": "publications.aap.org", "host": "publications.aap.org", "snippet": "For cases of CMC or intertrigo, the differential diagnosis includes erythrasma, seborrheic dermatitis, dermatitis enteropathica, syphilis, Gram-negative", "score": 0.53342235 }, { "number": 17, "title": "Seborrheic Dermatitis | Pediatric Care Online | American Academy of Pediatrics", "detail": "publications.aap.org", "url": "https://publications.aap.org/pediatriccare/article/doi/10.1542/aap.ppcqr.396224/96/Seborrheic-Dermatitis", "authors": "publications.aap.org", "host": "publications.aap.org", "snippet": "Point-of-Care Quick Reference|. # Seborrheic Dermatitis. Search for other works by this author on:. **Quick References** 2024; 10.1542/aap.ppcqr.396224. ## Key Points. * Seborrheic dermatitis (SD) is a generally benign dermatosis affecting infants and adolescents. * Affected areas commonly include t", "score": 0.5164741 }, { "number": 18, "title": "An Adolescent Male With Severe Facial Swelling and Scalp Infection", "detail": "publications.aap.org", "url": "https://publications.aap.org/pediatricsinreview/article/36/11/e39/34815/Visual-Diagnosis-An-Adolescent-Male-With-Severe", "authors": "publications.aap.org", "host": "publications.aap.org", "snippet": "A potassium hydroxide (KOH) or fungal culture from the hair shaft can confirm the diagnosis. Definitive diagnosis of allergic dermatitis", "score": 0.45377067 }, { "number": 19, "title": "A Comparison of Topical Corticosteroids and Topical Calcineurin Inhibitors for the Treatment of Atopic Dermatitis", "detail": "www.jaci-inpractice.org", "url": "https://www.jaci-inpractice.org/article/S2213-2198(23)00306-9/abstract", "authors": "www.jaci-inpractice.org", "host": "www.jaci-inpractice.org", "snippet": "A Comparison of Topical Corticosteroids and Topical Calcineurin Inhibitors for the Treatment of Atopic Dermatitis - The Journal of Allergy and Clinical Immunology: In Practice. A Comparison of Topical Corticosteroids and Topical Calcineurin Inhibitors for the Treatment of Atopic Dermatitis. * Contin", "score": 0.32366917 }, { "number": 20, "title": "[PDF] 2010 namcs micro-data file documentation - CDC", "detail": "ftp.cdc.gov", "url": "https://ftp.cdc.gov/pub/health_statistics/nchs/dataset_documentation/NAMCS/2010/doc2010.pdf", "authors": "ftp.cdc.gov", "host": "ftp.cdc.gov", "snippet": "Includes: Advanced maternal age (if age<35, use 3205.0) Diabetes during pregnancy Ectopic pregnancy Edema of pregnancy Fetal death in utero Gallstones High blood pressure during pregnancy High risk pregnancy Hyperemesis Intrauterine growth retardation (IUGR) Miscarriage (if patient is pregnant) Mult", "score": 0.1795165 }, { "number": 21, "title": "[PDF] 2011 National Hospital Ambulatory Medical Care Survey ... - CDC", "detail": "ftp.cdc.gov", "url": "https://ftp.cdc.gov/pub/health_statistics/nchs/dataset_documentation/NHAMCS/doc11.pdf", "authors": "ftp.cdc.gov", "host": "ftp.cdc.gov", "snippet": "d01265 SULFACETAMIDE SODIUM TOPICAL d01267 MUPIROCIN TOPICAL d01271 ECONAZOLE TOPICAL d01272 CICLOPIROX TOPICAL d01274 TOLNAFTATE TOPICAL d01277 NAFTIFINE TOPICAL d01278 LINDANE TOPICAL d01279 PERMETHRIN TOPICAL d01280 CROTAMITON TOPICAL d01282 ALCLOMETASONE TOPICAL d01288 CLOBETASOL TOPICAL d01289 ", "score": 0.16555294 }, { "number": 22, "title": "Malassezia yeasts in seborrheic dermatitis scalp in a ... - PubMed", "detail": "pubmed.ncbi.nlm.nih.gov", "url": "https://pubmed.ncbi.nlm.nih.gov/29484095", "authors": "pubmed.ncbi.nlm.nih.gov", "host": "pubmed.ncbi.nlm.nih.gov", "snippet": "Malassezia spp in skin microbiome scalp has been implicated in seborrheic dermatitis pathogenesis. Thus, treatment based in antifungal combined", "score": 0.7568076 }, { "number": 23, "title": "Seborrhoeic dermatitis - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3275327", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "The cause of seborrhoeic dermatitis is unknown. _Malassezia_ yeasts are thought to have an important role.\n\n The inflammatory process may be mediated in susceptible people by fungal metabolites, namely free fatty acids, released from sebaceous triglycerides. The lipid layer of _Malassezia_ can als", "score": 0.57837737 }, { "number": 24, "title": "Optimizing Treatment Approaches in Seborrheic Dermatitis - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3579488", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "Seborrheic dermatitis (SD), a chronic, recurrent, inflammatory condition characterized by erythema and skin flaking, may be resistant to treatment and often has a substantial negative impact on quality of life.1–3 It affects approximately six million people in the United States and is associated wit", "score": 0.5746579 } ], "publishedAt": "2026-09-15T23:47:26.978131+00:00", "updatedAt": "2026-09-15T23:47:26.978131+00:00", "readingMinutes": 5, "slug": "seborrheic-dermatitis" }