{ "schemaVersion": 2, "eyebrow": "Gastrointestinal Surgery", "title": "Ileus", "summary": "Manage suspected ileus by first excluding mechanical obstruction, ischemia, perforation, and acute colonic pseudo-obstruction. Correct reversible drivers, decompress selectively for vomiting or marked distention, minimize opioids, mobilize early, and escalate predominant colonic dilation to monitored neostigmine or endoscopic decompression.", "seoDescription": "Physician guide to diagnosing and managing ileus, distinguishing obstruction and Ogilvie syndrome, correcting precipitants, and escalating decompression.", "clinicalQuestion": "How should clinicians distinguish ileus from obstruction and pseudo-obstruction, stabilize patients, and select decompression or escalation?", "specialty": "Gastroenterology and General Surgery", "audience": "U.S. physicians and medical trainees", "tags": [ "ileus", "postoperative ileus", "adynamic ileus", "acute colonic pseudo-obstruction", "Ogilvie syndrome", "bowel obstruction", "neostigmine" ], "keyTakeaways": [ "Do not label postoperative distention as ileus until mechanical obstruction, bowel ischemia, and perforation have been considered; persistent or worsening obstruction requires surgical assessment rather than prolonged expectant management. [17]", "Predominant colonic dilation without mechanical obstruction suggests acute colonic pseudo-obstruction; small-bowel dilation accompanying colonic dilation favors postoperative ileus. [5]", "Initial treatment of functional obstruction is bowel rest when clinically indicated, isotonic IV fluid and electrolyte correction, removal of motility-inhibiting drugs, opioid minimization, and selective nasogastric decompression for emesis or gastric distention. [17][21][23]", "In acute colonic pseudo-obstruction refractory to conservative management, IV neostigmine 2 mg can produce colonic decompression but requires continuous cardiac monitoring because bradycardia, heart block, and serious arrhythmias may occur. [20][22]", "A colon diameter greater than 10 cm is associated with perforation risk in pseudo-obstruction and should prompt decompression planning rather than continued observation alone. [24]" ], "sections": [ { "id": "initial-triage", "eyebrow": "First Decision", "heading": "Identify obstruction, ischemia, or perforation before treating presumed ileus", "intro": "Functional obstruction is a diagnosis reached after excluding a structural or surgical cause.", "paragraphs": [ "Treat hemodynamic instability, peritonitis, suspected perforation, or concern for strangulation/ischemia as an urgent surgical problem. Begin isotonic IV fluid resuscitation and correct electrolyte abnormalities; use nasogastric decompression for clinically important vomiting, gastric distention, or aspiration risk. Mechanical small-bowel obstruction with strangulation, ischemia, or failure to resolve requires operative management. [17]", "In an adult with postoperative or acute inpatient distention, obtain abdominal imaging to define the distribution of bowel dilation and assess for a mechanical transition point or other obstructing lesion. Multiple dilated, fluid-filled bowel loops can represent either paralytic ileus or mechanical small-bowel obstruction, so radiographic dilation alone does not establish functional disease. [13]", "Do not use passage of stool or flatus as reassurance when abdominal distention is progressing. A reported pseudo-obstruction case developed marked enlargement despite regular bowel movements and flatus after conservative treatment; serial examination and repeat assessment of abdominal girth or colonic diameter should drive escalation. [23]" ], "bullets": [ "Immediately assess volume status, vomiting/aspiration risk, abdominal tenderness or peritoneal signs, medication exposures, recent operation or trauma, severe systemic illness, and electrolyte or metabolic derangements. [17][23]", "Use lactated Ringer solution or normal saline for intravascular depletion associated with third spacing, emesis, or reduced oral intake; correct hypokalemia and other electrolyte abnormalities concurrently. [17]", "With bilious vomiting in an infant, presume bowel obstruction until proved otherwise and obtain urgent pediatric surgical review; this is not a setting for a presumptive diagnosis of ileus. [15][16]" ], "subsections": [], "table": { "caption": "Initial pattern recognition for functional versus mechanical bowel obstruction. [5][13][17]", "columns": [ "Clinical-radiographic pattern", "Interpretation", "Immediate next action" ], "rows": [ [ "Diffuse bowel dilation with air-fluid levels", "Compatible with paralytic ileus but may overlap with mechanical small-bowel obstruction. [13]", "Assess for a mechanical cause; resuscitate, correct electrolytes, and decompress selectively for vomiting or gastric distention. [17]" ], [ "Colonic dilation without mechanical obstruction", "Acute colonic pseudo-obstruction is likely. [12]", "Remove precipitating factors, monitor colonic diameter, and plan decompression if conservative management fails or dilation is high risk. [20][24]" ], [ "Colonic dilation plus small-bowel dilation after surgery", "Pattern used to classify postoperative ileus rather than isolated colonic pseudo-obstruction. [5]", "Treat reversible contributors and reassess if symptoms or distention worsen. [17][23]" ], [ "Mechanical obstruction with ischemia, strangulation, or lack of resolution", "Structural obstruction requiring definitive management. [17]", "Urgent surgical management. [17]" ] ] } }, { "id": "distinguish-pseudo-obstruction", "eyebrow": "Critical Branch", "heading": "Separate postoperative ileus from acute colonic pseudo-obstruction", "intro": "The distribution of dilation changes the treatment pathway.", "paragraphs": [ "Postoperative ileus is commonly driven by recent surgical inflammation and opioid analgesia; it occurs in up to 50% of patients after abdominal surgery. Initial management is directed at removing the precipitant, particularly replacing opioid analgesia with nonopioid options where feasible, while encouraging ambulation and using nasogastric decompression if worsening emesis or distention develops. [24]", "Acute colonic pseudo-obstruction (Ogilvie syndrome) is colonic dysmotility with colonic distention in the absence of mechanical obstruction. It occurs after surgery or trauma in approximately 50% to 60% of reported cases and is associated with older age, immobility or neurologic impairment, opioid exposure, infection, metabolic disorders, extensive surgery, and medications that inhibit intestinal motility. [5][9][24]", "Measure and trend the maximal colonic diameter when acute colonic pseudo-obstruction is suspected. A colon greater than 10 cm is described as at risk for perforation, with the cecum particularly vulnerable because it has the largest radius; this threshold should trigger active decompression planning after exclusion of mechanical obstruction. [24]" ], "bullets": [ "Favor postoperative ileus when both small bowel and colon are dilated after surgery. [5]", "Favor acute colonic pseudo-obstruction when imaging shows predominant colonic dilation without an obstructing lesion. [5][12]", "Do not treat presumed pseudo-obstruction with neostigmine until a mechanical obstruction has been excluded. [12][22]" ], "subsections": [ { "heading": "Recurrent or refractory colonic dilation", "paragraphs": [ "For recurrent symptoms despite medical and endoscopic management of acute colonic pseudo-obstruction, reconsider whether the patient has an underlying colonic functional disorder, including slow-transit dysmotility or chronic intestinal pseudo-obstruction, rather than repeated isolated acute episodes. [12]" ], "bullets": [] } ], "table": { "caption": "Functional-obstruction phenotypes and management implications. [5][9][12][24]", "columns": [ "Feature", "Postoperative ileus", "Acute colonic pseudo-obstruction" ], "rows": [ [ "Predominant dilation pattern", "Small-bowel dilation with colonic dilation supports postoperative ileus. [5]", "Colonic dilation without mechanical obstruction. [12]" ], [ "Common setting", "Recent abdominal surgery; inflammatory mediators and opioid analgesia contribute. [24]", "Surgery, trauma, severe illness, metabolic disorders, motility-inhibiting medications, older age, and immobility. [5][9][24]" ], [ "Initial intervention", "Reduce or replace opioids, correct reversible abnormalities, mobilize, and consider nasogastric decompression for worsening emesis. [17][24]", "Correct fluid, electrolyte, and metabolic triggers; stop opioids and anticholinergic agents; keep NPO during active distention and decompress if conservative care fails. [20][23]" ], [ "Escalation pathway", "Reevaluate for mechanical obstruction or other surgical pathology if symptoms progress or fail to resolve. [17]", "For refractory disease, use monitored neostigmine or colonoscopic decompression; consider recurrence as a signal for chronic dysmotility. [12][20][22]" ] ] } }, { "id": "supportive-management", "eyebrow": "Immediate Management", "heading": "Correct reversible drivers and use selective decompression", "intro": "Supportive treatment should target the mechanism maintaining dysmotility rather than simply delay intervention.", "paragraphs": [ "Place patients with clinically significant ileus or pseudo-obstruction on bowel rest while treating the precipitating condition. Replace fluid, electrolyte, and metabolic deficits, and discontinue or reduce medications that impair motility, especially opioids and anticholinergic agents. For postoperative ileus, changing pain treatment from opioid to nonopioid analgesia is an early intervention; for pseudo-obstruction, wean narcotics to the lowest dose that provides acceptable analgesia. [17][23][24]", "Use nasogastric decompression selectively for gastric distention, persistent vomiting, or aspiration risk; it relieves distention and vomiting but does not correct the underlying dysmotility. In pseudo-obstruction conservative care, nasogastric suction, NPO status, IV fluids, electrolyte replacement, avoidance of offending medications, frequent repositioning, and ambulation are used while serially reassessing distention. [17][20][23]", "For postoperative prevention and recovery, implement the relevant components of an enhanced-recovery pathway: minimally invasive surgery when feasible, optimized fluid management, opioid-sparing analgesia, early mobilization, early postoperative food intake when not contraindicated, laxatives, and omission or early removal of postoperative nasogastric intubation. The ERAS emergency-laparotomy guideline rates this multifaceted approach as a strong recommendation with moderate-quality evidence. [19]" ], "bullets": [ "Review medication administration records for opioid and anticholinergic exposure; actively stop, reduce, or substitute these agents when clinically possible. [23][24]", "Track abdominal examination, emesis, nasogastric output when present, electrolyte replacement, and imaging-defined bowel or colon caliber rather than relying on a single bedside finding. [17][23]", "Reintroduce oral or enteral nutrition as gastrointestinal function recovers and contraindications resolve; if enteral feeding remains contraindicated, early parenteral nutrition may be indicated after emergency laparotomy. [19]" ], "subsections": [], "table": { "caption": "Actionable supportive-management bundle for ileus and pseudo-obstruction. [17][19][23][24]", "columns": [ "Action", "When to use it", "Operational target" ], "rows": [ [ "Isotonic IV fluid and electrolyte correction", "Volume depletion, emesis, third spacing, hypokalemia, or other metabolic abnormalities. [17][23]", "Restore intravascular volume and correct abnormalities that perpetuate dysmotility. [17][23]" ], [ "Opioid reduction or substitution", "Postoperative ileus or pseudo-obstruction with opioid exposure. [23][24]", "Use nonopioid analgesia where feasible; otherwise reduce narcotics to the lowest effective dose. [23][24]" ], [ "Nasogastric tube", "Vomiting, gastric distention, or aspiration risk. [17]", "Decompress the stomach while reassessing for a structural cause or need for escalation. [17][23]" ], [ "Mobilization and repositioning", "Hemodynamically stable postoperative patients and patients with functional obstruction. [19][23]", "Support recovery of gut function and reduce postoperative ileus burden. [19]" ], [ "Bowel rest, then nutrition reassessment", "Active symptomatic ileus or pseudo-obstruction; resume intake when function recovers. [19][23]", "Avoid enteral intake during unresolved functional obstruction; use parenteral nutrition when enteral feeding is contraindicated after emergency laparotomy. [19]" ] ] } }, { "id": "pseudo-obstruction-escalation", "eyebrow": "Escalation", "heading": "Use neostigmine or endoscopic decompression for refractory acute colonic pseudo-obstruction", "intro": "Escalation applies to confirmed colonic pseudo-obstruction after conservative measures and exclusion of mechanical obstruction.", "paragraphs": [ "For acute colonic pseudo-obstruction refractory to conservative management, administer neostigmine 2 mg intravenously in a monitored setting. In a randomized placebo-controlled trial of 21 patients, IV neostigmine produced effective colonic decompression in refractory disease. [22]", "Continuous cardiac monitoring is required during neostigmine administration because the drug can cause bradycardia, heart block, and life-threatening arrhythmias. These adverse effects are the principal operational limitation of pharmacologic decompression. [20]", "Use colonoscopic decompression when decompression is needed and neostigmine is unsuitable, unavailable, or unsuccessful. Endoscopic decompression is an established specific therapy for acute colonic pseudo-obstruction; other described nonsurgical approaches include fluoroscopically guided decompression tubes and percutaneous cecostomy through endoscopic, laparoscopic, or surgical approaches. [9][23]", "Escalate beyond medical or endoscopic management if perforation, peritonitis, or a mechanical process is identified. Do not redirect a patient with suspected ischemia, strangulation, or unresolved mechanical obstruction into an ileus pathway. [17]" ], "bullets": [ "Before neostigmine: confirm a pseudo-obstructive colonic pattern and exclude mechanical obstruction. [12][22]", "During neostigmine: use continuous cardiac monitoring because of bradyarrhythmic risk. [20]", "After failure or recurrence: reassess colonic diameter, repeat the diagnostic review for structural disease, and consider chronic dysmotility in recurrent cases. [12][23]" ], "subsections": [], "table": { "caption": "Escalation choices for acute colonic pseudo-obstruction. [9][12][20][22][23][24]", "columns": [ "Clinical situation", "Preferred escalation", "Key limitation or monitoring" ], "rows": [ [ "Confirmed ACPO refractory to conservative management", "Neostigmine 2 mg IV. [22]", "Continuous cardiac monitoring for bradycardia, heart block, and potentially life-threatening arrhythmia. [20]" ], [ "High-risk colonic dilation", "Plan decompression when colon diameter exceeds 10 cm. [24]", "Confirm absence of mechanical obstruction before pharmacologic decompression. [12][22]" ], [ "Neostigmine unsuitable, unavailable, or unsuccessful", "Colonoscopic decompression. [9][23]", "Maintain correction of precipitating factors and monitor for recurrent distention. [23]" ], [ "Peritonitis, perforation, ischemia, strangulation, or mechanical obstruction", "Urgent surgical evaluation and definitive management. [17]", "Do not manage as uncomplicated functional obstruction. [17]" ] ] } }, { "id": "postoperative-prevention-monitoring", "eyebrow": "Perioperative Care", "heading": "Prevent postoperative ileus and monitor for diagnostic drift", "intro": "Prevention is most effective when embedded in perioperative care rather than added after established distention.", "paragraphs": [ "For patients undergoing emergency laparotomy, use a bundled ileus-prevention strategy rather than a single intervention: minimally invasive approaches when feasible, optimized fluid administration, opioid-sparing analgesia, early mobilization, early postoperative feeding when clinically permissible, laxatives, and avoidance or early removal of a nasogastric tube. [19]", "If a presumed postoperative ileus worsens after initial opioid reduction, ambulation, electrolyte correction, and selective gastric decompression, reopen the structural differential rather than repeatedly adding promotility agents. Worsening emesis, increasing distention, or failure to improve should trigger reassessment for mechanical obstruction and surgical complications. [17][24]", "After bowel surgery or emergency laparotomy, advance oral or enteral nutrition when gastrointestinal function recovers and contraindications have ended. When enteral feeding cannot be used, early parenteral nutrition is recommended to mitigate inadequate intake, with transition back to oral or enteral feeding once caloric needs can be met safely. [19]" ], "bullets": [ "Avoid routine prolonged postoperative nasogastric intubation; omit it or remove it early when clinically appropriate. [19]", "Use opioid-sparing analgesia as both an analgesic strategy and an ileus-prevention intervention. [19][24]", "Escalate recurrent pseudo-obstruction after medical or endoscopic therapy to evaluation for slow-transit dysmotility or chronic intestinal pseudo-obstruction. [12]" ], "subsections": [], "table": { "caption": "Monitoring findings that should change the ileus management plan. [12][17][19][23][24]", "columns": [ "Finding", "Interpretation", "Action" ], "rows": [ [ "Improving emesis and distention with recovering gastrointestinal function", "Supports recovery of functional obstruction. [19]", "Resume oral or enteral intake when safe; remove parenteral support once caloric needs are met enterally or orally. [19]" ], [ "Increasing abdominal girth or persistent marked colonic dilation", "May represent progressive acute colonic pseudo-obstruction despite stool or flatus. [23]", "Trend colonic diameter and escalate to monitored neostigmine or endoscopic decompression when indicated. [20][22][24]" ], [ "Colon diameter greater than 10 cm", "Higher perforation risk in pseudo-obstruction. [24]", "Arrange decompression rather than continued observation alone. [24]" ], [ "Persistent or worsening symptoms after initial ileus treatment", "Raises concern for mechanical obstruction or a surgical complication. [17]", "Repeat diagnostic assessment and obtain urgent surgical input when ischemia, strangulation, or unresolved obstruction is suspected. 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Verify recommendations against current guidance and patient-specific factors.", "citations": [ { "number": 1, "title": "[PDF] 203952Orig1s000 - accessdata.fda.gov", "detail": "www.accessdata.fda.gov", "url": "https://www.accessdata.fda.gov/drugsatfda_docs/nda/2015/203952Orig1s000MedR.pdf", "authors": "www.accessdata.fda.gov", "host": "www.accessdata.fda.gov", "snippet": "2 (5.4) 0 0 0 Vomiting 2 (7.4) 0 2 (5.4) 0 1 (5.3) 1 (2.9) Pyrexia 2 (7.4) 0 2 (5.4) 0 0 0 Postoperative ileus 2 (7.4) 0 2 (5.4) 0 0 0 Anxiety 1 (3.7) 1 (10.0) 2 (5.4) 0 0 0 Reference ID: 3469235 Clinical Review Leonard. P. Kapcala, M.D. [...] state 3 (11.1) 0 3 (8.1) 0 1 (5.3) 1 (2.9) Atelectasis 1", "score": 0.5806618 }, { "number": 2, "title": "[PDF] NDA Inter-Disciplinary Review and Evaluation - accessdata.fda.gov", "detail": "www.accessdata.fda.gov", "url": "https://www.accessdata.fda.gov/drugsatfda_docs/pediatric/419_203441%20S-013_teduglutide_Unireview%20prea.pdf", "authors": "www.accessdata.fda.gov", "host": "www.accessdata.fda.gov", "snippet": "7HUPV\u0012 Verbatim Term $FWLRQ 7DNHQ :LWK 6WXG\\ 'UXJ 2XWFRPH 7('\u0010&\u0014\u0017\u0010\u0013\u0013\u0019 62& DUP ,OHXV SDUDO\\WLF\u0012 Paralytic ileus 'UXJ LQWHUUXSWHG DQG UHVWDUWHG 5HVROYHG 6+3\u0019\u0016\u0016\u0010\u0016\u0013\u0017 177\u00127(' 7('\u0010&\u0014\u0017\u0010\u0013\u0013\u0019 7(' \u0013\u0011\u0013\u0018 PJ\u0012NJ\u0012GD\\ 6+3\u0019\u0016\u0016\u0010\u0016\u0013\u0017 7('\u00127(' 3RVWRSHUDWLYH LOHXV\u0012 Postanesthesia ileus 'UXJ LQWHUUXSWHG GXH WR HYHQW 5HVROYHG", "score": 0.42734948 }, { "number": 3, "title": "[PDF] Hyaluronic Acid (HA): Medical Device Material Safety Summary - FDA", "detail": "www.fda.gov", "url": "https://www.fda.gov/media/158489/download", "authors": "www.fda.gov", "host": "www.fda.gov", "snippet": "and Bulking Agent Applications Application Local Host Responses/Device Events Quality of Evidence (local responses) Systemic Responses Quality of Evidence (systemic responses) Hyaluronic Acid as a material (1 human study, no animal studies) Hematuria, nausea Low Urticaria Low Adhesion barrier (34 hu", "score": 0.18181492 }, { "number": 4, "title": "[PDF] 215019Orig1s000 INTEGRATED REVIEW - accessdata.fda.gov", "detail": "www.accessdata.fda.gov", "url": "https://www.accessdata.fda.gov/drugsatfda_docs/nda/2022/215019Orig1s000IntegratedR.pdf", "authors": "www.accessdata.fda.gov", "host": "www.accessdata.fda.gov", "snippet": "(global incidence of 1 case per 1000 person-years). • Not disabling, but pain and dietary restrictions can impact quality of life. • Complications include perforation, gastric outlet obstruction, and bleeding, which can be life-threatening. • Most common causes of peptic ulcer disease are Helicobact", "score": 0.11347172 }, { "number": 5, "title": "Ogilvie Syndrome as a Postoperative Complication", "detail": "jamanetwork.com", "url": "https://jamanetwork.com/journals/jamasurgery/fullarticle/390622", "authors": "jamanetwork.com", "host": "jamanetwork.com", "snippet": "Our data confirm that patients undergoing orthopedic and spinal procedures are at higher risk, but that the surgical procedure most commonly leading to Ogilvie syndrome was coronary artery bypass grafting. Agents that increase parasympathetic tone have been shown to resolve pseudo-obstruction withou", "score": 0.65412235 }, { "number": 6, "title": "VA AT IO N", "detail": "academic.oup.com", "url": "https://academic.oup.com/ajhp/article-pdf/14/6/619/28274291/ajhp0619.pdf", "authors": "academic.oup.com", "host": "academic.oup.com", "snippet": "for paralytic ileus and urinary retention after ganglionic blockage (Jan.-Feb.) low toxicity. High quality, dependable Barnstead Q- and pyloric obstruction.", "score": 0.33189937 }, { "number": 7, "title": "insights from the SPRING-SIR national Italian registry | Rheumatology", "detail": "academic.oup.com", "url": "https://academic.oup.com/rheumatology/article/65/1/keaf457/8248581", "authors": "academic.oup.com", "host": "academic.oup.com", "snippet": "... paralytic ileus and intestinal pseudo-obstruction [4]. In SSc, GI involvement is not only a source of considerable discomfort but also contributes", "score": 0.31875068 }, { "number": 8, "title": "Acute appendicitis causing small bowel obstruction - Oxford Academic", "detail": "academic.oup.com", "url": "https://academic.oup.com/jscr/article/2025/10/rjaf809/8277756", "authors": "academic.oup.com", "host": "academic.oup.com", "snippet": "Adynamic obstruction (paralytic ileus) is the most common, arising from the inflammatory spread to adjacent structures such as the cecum, small", "score": 0.28149495 }, { "number": 9, "title": "Adynamic Ileus and Acute Colonic Pseudo-Obstruction - ScienceDirect", "detail": "www.sciencedirect.com", "url": "https://www.sciencedirect.com/science/article/pii/S0025712508000035", "authors": "www.sciencedirect.com", "host": "www.sciencedirect.com", "snippet": "# Adynamic Ileus and Acute Colonic Pseudo-Obstruction. Ileus and colonic pseudo-obstruction cause functional obstruction of intestinal transit, without mechanical obstruction, because of uncoordinated or attenuated intestinal muscle contractions. Colonic pseudo-obstruction is induced by numerous met", "score": 0.38228035 }, { "number": 10, "title": "The acute contrast enema in suspected large bowel obstruction: Value and technique - ScienceDirect", "detail": "www.sciencedirect.com", "url": "https://www.sciencedirect.com/science/article/abs/pii/S0009926005801709", "authors": "www.sciencedirect.com", "host": "www.sciencedirect.com", "snippet": "### Colonic ileus\n\n### Gastrointestinal Radiology\n\n### Functional evaluation of the acute abdomen by radiological means\n\n### CRC Critical Reviews in Radiological Sciences\n\n## Cited by (83)\n\n### Mechanical Obstruction of the Small Bowel and Colon\n\n### Bowel obstruction: A narrative review for all phy", "score": 0.36779293 }, { "number": 11, "title": "Colonic pseudo-obstruction following termination of pregnancy and uterine operation - ScienceDirect", "detail": "www.sciencedirect.com", "url": "https://www.sciencedirect.com/science/article/abs/pii/0002937876904567", "authors": "www.sciencedirect.com", "host": "www.sciencedirect.com", "snippet": "Elsevier logo\nAmerican Journal of Obstetrics and Gynecology\n\n## American Journal of Obstetrics and Gynecology\n\n## Published by: Elsevier\n\n### Published by\n\nElsevier\n\n# Colonic pseudo-obstruction following termination of pregnancy and uterine operation\n\n## Article preview\n\n## Abstract\n\n## Organizatio", "score": 0.16506785 }, { "number": 12, "title": "Acute Colonic Pseudo-Obstruction - PubMed", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/pubmed/35966377", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov", "snippet": "Title: Acute Colonic Pseudo-Obstruction - PubMed\nSkip to main page content. An official website of the United States government. **The .gov means it’s official.**. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government si", "score": 0.39194164 }, { "number": 13, "title": "[PDF] Good clinical diagnostic practice", "detail": "applications.emro.who.int", "url": "https://applications.emro.who.int/dsaf/dsa236.pdf", "authors": "applications.emro.who.int", "host": "applications.emro.who.int", "snippet": "up; left and right decubitus; and a chest X-ray to look for fluid levels. It may be possible to determine the level of obstruction (jejunum, ileum, colon). Intestinal obstruction caused by a large bowel volvulus may be identified. Fluid levels at all levels of the bowel are seen in paralytic ileus. ", "score": 0.2899549 }, { "number": 14, "title": "[PDF] ICD-11 Reference Guide - World Health Organization (WHO)", "detail": "icdcdn.who.int", "url": "https://icdcdn.who.int/icd11referenceguide/en/refguide.pdf", "authors": "icdcdn.who.int", "host": "icdcdn.who.int", "snippet": "respiratory Mediastinitis Obstruction, upper airway OCPR Oedema, laryngeal OCPR Oedema/hypostasis, pulmonary Pneumonia Pneumothorax OCPR Gastrointestinal complications Flag Abscess, intra-abdominal OCPR Constipation OCPR Dilatation, gastric OCPR Disorder, circulatory, gastrointestinal OCPR Embolism,", "score": 0.14025407 }, { "number": 15, "title": "[PDF] Hospital care for children - WHO | Regional Office for Africa", "detail": "www.afro.who.int", "url": "https://www.afro.who.int/sites/default/files/2017-06/pocket_booklet_hospital_care_0.pdf", "authors": "www.afro.who.int", "host": "www.afro.who.int", "snippet": "9.2.2 Bowel obstruction in the newborn May be due to hypertrophic pyloric stenosis, bowel atresia, malrotation with volvulus, meconium plug syndrome, Hirschsprung’s disease (colonic agangli-onosis), or imperforate anus.\nDiagnosis ■The level of obstruction determines the clinical presentation. Proxim", "score": 0.07769257 }, { "number": 16, "title": "[PDF] Hospital care for children - IRIS", "detail": "iris.who.int", "url": "https://iris.who.int/server/api/core/bitstreams/8f110da0-22e6-4ef1-90e4-c9f1b7daa363/content", "authors": "iris.who.int", "host": "iris.who.int", "snippet": "9.2.2 Bowel obstruction Bowel obstruction in a newborn may be due to hypertrophic pyloric steno-sis, bowel atresia, malrotation with volvulus, meconium plug syndrome, Hirschsprung disease (colonic aganglionosis) or imperforate anus. Diagnosis • The level of obstruction determines the clinical presen", "score": 0.07240695 }, { "number": 17, "title": "Small Bowel Obstruction - StatPearls - NCBI Bookshelf - NIH", "detail": "www.ncbi.nlm.nih.gov", "url": "https://www.ncbi.nlm.nih.gov/books/NBK448079", "authors": "www.ncbi.nlm.nih.gov", "host": "www.ncbi.nlm.nih.gov", "snippet": "Initial management includes fluid resuscitation, electrolyte correction, and nasogastric decompression, with surgery indicated for strangulation, ischemia, or unresolved obstruction. [...] Postoperative Care\n\nPostoperative care involves close monitoring for complications such as infection, anastomot", "score": 0.542161 }, { "number": 18, "title": "Diseases of the Alimentary Tract", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC7167529", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "Management of postoperative ileus and ileus associated with proximal duodenitis–jejunitis (anterior enteritis) includes correction of fluid and electrolyte abnormalities, relief of gastric distension, and administration of prokinetic drugs. Lidocaine (lignocaine, loading dose 1.5 mg/kg followed by 0", "score": 0.48689327 }, { "number": 19, "title": "Consensus Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS®) Society Recommendations Part 2—Emergency Laparotomy: Intra- and Postoperative Care - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC10241558", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "| 33.2 | If enteral feeding is contraindicated, early parenteral nutrition is indicated to mitigate the period of inadequate oral/enteral intake. Enteral or oral nutrition may be reinitiated as gastrointestinal function recovers and/or contraindications end and replace parenteral nutrition when calo", "score": 0.4854295 }, { "number": 20, "title": "Neostigmine and glycopyrronium: a potential safe alternative for patients with pseudo-obstruction without access to conventional methods of decompression - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC5604700", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "Neostigmine methylsulfate is a reversible cholinesterase inhibitor, which is indicated in the management of symptomatic myasthenia gravis and in general anaesthesia for the reversal of non-depolarising neuromuscular agents.2 Neostigmine is effective in the treatment of ileus and pseudo-obstruction. ", "score": 0.48499045 }, { "number": 21, "title": "Prevention and Management of Postoperative Ileus: A Review of Current Practice - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC8963477", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "Prevention of POI improves recovery and reduces hospital stay. This has been evident with the introduction of enhanced ERAS and minimally invasive surgery. Moreover, standard management of POI includes correction of reversible surgical and medical causes with supportive measures of pain control, int", "score": 0.48323447 }, { "number": 22, "title": "Neostigmine for acute colonic pseudo–obstruction: New use for an old drug? - Gastroenterology", "detail": "www.gastrojournal.org", "url": "https://www.gastrojournal.org/article/S0016-5085(00)70229-0/fulltext", "authors": "www.gastrojournal.org", "host": "www.gastrojournal.org", "snippet": "# Neostigmine for acute colonic pseudo–obstruction: New use for an old drug? Neostigmine for the treatment of acute colonic pseudo-obstruction. Twenty-one patients with acute colonic pseudo-obstruction were randomized to receive either 2 mg neostigmine or saline intravenously. The investigators conc", "score": 0.73846215 }, { "number": 23, "title": "Neostigmine to Relieve a Suspected Colonic Pseudo-Obstruction in a Burn Patient: A Case-Based Review of the Literature - PMC", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3549582", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "The major principle underlying conservative therapy is the identification and treatment of the underlying causative factors. Correction of electrolyte, fluid, and metabolic imbalances are vital. Patients should be kept nil per os until ileus resolves. Decompression of the stomach via nasogastric suc", "score": 0.47548413 }, { "number": 24, "title": "Question Sets and Answers - PMC - NIH", "detail": "pmc.ncbi.nlm.nih.gov", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC7120678", "authors": "pmc.ncbi.nlm.nih.gov", "host": "pmc.ncbi.nlm.nih.gov", "snippet": "bowel decompression including a NGT (B) can be considered. Returning to the OR for exploration (E) is inappropriate for postoperative ileus. Neostigmine is used in patients with pseudo-obstruction (Ogilvie’s syndrome). [...] Always consider a nonmechanical postoperative ileus in patients that have h", "score": 0.4011956 } ], "publishedAt": "2026-09-16T01:04:57.391776+00:00", "updatedAt": "2026-09-16T01:04:57.391776+00:00", "readingMinutes": 6, "slug": "ileus" }