Astra

A unified medical intelligence workspace for bedside decision‑making

Clinical Rationale

Busy clinicians encounter four persistent pain‑points at the bedside:

  1. Evidence retrieval — "What does the most relevant guideline or RCT say for this patient?"
  2. Diagnostic reasoning — weighing pre‑test probability, likelihood ratios, and competing differentials in real time.
  3. Therapeutic planning — translating evidence into concise, actionable orders the team can follow.
  4. Documentation — producing a note that stands up to attending‑level scrutiny.

Astra brings these steps together in a unified interface backed by retrieval‑augmented language models and structured citation checks.

What You Can Do Today

Search

Pose PICO‑style questions like "For septic shock in adults, does early vasopressin improve mortality?" Astra returns a succinct synthesis of landmark trials and systematic reviews with inline PubMed IDs.

Reason

Feed an undifferentiated presentation (e.g., dyspnea in the ED). Astra outputs a Bayesian differential with pre‑/post‑test probabilities, recommended next tests, and a problem‑oriented Plan referencing seminal studies (ARDSnet, PROSEVA).

Write

Convert a bedside impression—such as a post‑op Day 2 update—into a structured Assessment & Plan that includes suggested orders, monitoring parameters, and follow‑up labs.

Under the Hood

  • Retrieval‑augmented reasoning — Queries are decomposed into PICO elements, matched against ~500 embedded landmark trials using cosine similarity, then fed into transformer models tuned for clinical tasks.
  • Evidence linker — Every recommendation must cite a verifiable PMID or DOI; responses fail validation if a citation cannot be matched.
  • Bayesian engine — Likelihood ratios and prevalence estimates are converted into post‑test probabilities inline.
  • Data & auth — Chat history and embeddings reside in an encrypted relational store with row‑level security; all API calls are gated by OpenID‑Connect SSO tokens.

Security & Compliance

Transport TLS 1.3 on every hop
Storage AES‑256 encryption at rest; daily encrypted backups
Access Role‑based policies, row‑level security
Runtime Isolated server‑side execution; secrets never leave the server
Audit Immutable logs retained ≥ 30 days

Current Limitations

  • Ultra‑rare adverse effects and local formulary nuances may be missing—verify critical orders.
  • The literature index refreshes every few hours; very recent pre‑prints may not appear immediately.
  • Astra supplements clinical judgment; it does not override institutional policy.

Roadmap

  • Bidirectional EHR connector for one‑click note insertion and order drafts.
  • Real‑time drug–drug interaction checker within the Plan.
  • Practice‑gap analytics derived from de‑identified usage trends.
Astra exists to lighten cognitive load: faster evidence, clearer reasoning, and notes that withstand peer review.

Business & Contact

Astraeus Intelligence LLC

254 Chapman Rd, Ste 208

Newark, Delaware 19702

support@astramd.org